Background: In this prospective study, we aimed to compare the intraoperative complication rates, operation time, preoperative-postoperative AMH and hemoglobin values, and the length of hospital stay for the patients undergoing elective laparoscopic myomectomy made or not made with uterine artery and ovarian artery ligation. Methods: In this prospective clinical study, 32 patients undergoing elective laparoscopic myomectomy were divided in two groups as ligated and non-ligated. Primer outcome was determined according to different preoperative-postoperative haemoglobin to determine blood loss in patients. Seconder outcomes were determined as intraoperative complication rates, operation time, preoperative-postoperative AMH and the length of hospital stay. Results: Similar demographic characteristics were found for both groups (ligated and non-ligated). Additionally, myoma localization, age (39±5 vs 41.2±3.8), preop haemoglobin (12.7±0.9 vs 12.6 ±1.3), preop and postop AMH (1.9 ±2.2 and 2 ±2.1 vs 1.1 ±1.7 and 1.1 ±1.3) and operation time (69 ±17 vs 75.3 ± 19) were similar, while postoperative haemoglobin values (10.4±1.1 vs 11.4±1.3) were significantly higher for ligated group than non-ligated when compared. Conclusions: It was observed that the loss of perioperative and postoperative hemoglobin value is decreased by ligation of uterine and ovarian arteries during and after the laparoscopic myomectomy without causing any important change of the operation time and AMH values.

Background: This review, was carried out to examine the effects of different positions on sleepwake states in preterm infants in a randomized controlled and quasi-experimental design nursing study results. Materials and Methods: This study is a systematic review. For this purpose, 5 databases including PubMed, MEDLINE, Google Scholar, Science Direct and Cochrane were scanned by matching with the keywords “preterm, sleep, position, infant, sleep-wakefulness”. All related English studies published in the literature between 1999-2022 were included in the evaluation. Results: In this study, a total of 1033 records were reached as a result of scanning the databases. A total of 11 publications that met the inclusion criteria were included in the study and evaluated in terms of results. It has been determined that positions are generally given during invasive procedures, after care and feedings, in order to improve the sleep of preterm infants. Positions given include hammock, nesting, facilitated fetal tucking, right or left lateral, supine and prone positions. Conclusions: It has been determined that the sleep-wake status of preterm infants is affected by positions. It has been determined that prone, hammock and facilitated fetal tucking positions can be given to improve the sleep-wake status of preterm infants receiving care in neonatal intensive care units.

Background: Coronavirus Disease 2019 (COVID-19) pandemic has affected many countries from dif-ferent aspects since December 2019. The present study aims to determine the frequency of prenatal de-pression risk and anxiety and associated risk factors in pregnant women as a vulnerable group in the COVID-19 Pandemic.Materials and Methods: This cross-sectional study included 234 pregnant women selected by cluster sampling method from all Primary Care Outpatient Clinics in Nigde. After ethics committee approval and institution permission was obtained, the data were collected online using the "Edinburgh Postpartum Depression Scale", "State and Trait Anxiety Index (STAI)" and a sociodemo-graphic questionnaire.Results: In the present study, the frequency of prenatal depression risk was 24.4%. The median value of the STAI trait score was 41 (23-74), and the median value of the STAI state was 34 (20-80). Prenatal depression risk was associated with job loss (OR: 2.68), multiple pregnancies (OR: 15.31), high COVID-19 perceived risk score (OR: 1.14), and high STAI state score (OR: 1.10) (p <0.05). Prenatal anxiety was associated with being a healthcare worker (OR: 11.66), smoking (OR: 17.21), having health problems during last pregnancy (OR: 3.74), thought of the people living with her at risk (OR: 2.48), and being depressed (OR: 4.73) (p <0.05).Conclusion: The COVID-19 Pandemic has been increasing the prevalence of depression risk and anxiety in pregnant women. It is essential to continue routine visits to healthcare centers taking necessary preventive measures and providing psychosocial support to pregnant women.

Background: Mechanical ventilation (MV) therapy can increase oxidative stress in the lungs. Oxidative stress can cause damage to collagen, an important component of the extracellular matrix in the lungs. In this study, total oxidative (TOS) and antioxidative (TAS) status in serum and bronchoalveolar lavage (BAL) were determined in patients who underwent MV. Our aim in the study was to determine whether there is a relationship between MV duration and oxidative stress parameters and prolidase, a collagen turn-over marker, in serum and BAL. Materials and Methods: The study included 26 adult patients aged 30-70 years, without primary lung pathology, and who were treated with MV for respiratory failure. TOS-TAS and prolidase enzyme activity were studied to determine oxidative stress levels in blood and BAL samples taken from patients on days 1-3-5. The oxidative stress index (OSI) was found by calculating the TOS/TAS ratio. Results: As the MV treatment period of the patients gets longer, in the serum; It was observed that OSI and prolidase levels increased significantly (p<0.01). Also in BAL; It was determined that the TAS decreased significantly, the OSI increased significantly and the prolidase level decreased significantly (p<0.001). Conclusion: Depending on the duration of MV therapy, increased oxidants (and decreased antioxidant capacity) in serum and BAL cause collagen tissue damage in the lungs. Prolidase in serum has also increased as an indicator of collagen damage in the lungs. We think that serum prolidase activity can be used as a viable test in order to detect and control MV-induced lung injury at an earlier stage.

Background: In this study it is aimed to compare the effects of Dexmedetomidine (Dex) and Thymoquinone (TQ) on kidney at hind limb ischemia/reperfusion injury generated rats Materials and Methods: 50 Wistar albino rats were included to the study. Rats were divided into 5 groups (n=10) as Sham, Control, TQ, Dex, and Dex-TQ. After anesthesia was given to the rats, ischemia was performed to left hind limb for 4 hours and then 2 hours reperfusion applied. TQ and Dex were administered intraperitoneally after the end of 4 hours ischemia and 5 minutes before start of reperfusion. At the end of study all rats were sacrificed. Blood and kidney samples were taken to evaluate Total Antioxidant Status (TAS), Total Oxidant Status (TOS) Oxidative Stress Index (OSI) values and histopathological examination. Results: TAS value was measured that the lowest value in Control Group (0.07±0.01). TAS values of TQ, Dex, Dex-TQ groups were significantly higher than those of Control Group (p<0.05). There was no significant difference between TQ, Dex, Dex-TQ groups regarding to TAS values (p>0.05). TOS values were measured and they were the highest in the Control Group and the lowest in the Sham Group (p<0.05 for all). TOS values of TQ, Dex, Dex-TQ groups significantly lower than those of the Control Group (p<0.05) and significantly higher than those of the Sham Group (p<0.05). There was no significant difference between TQ, Dex, Dex-TQ groups regarding to TOS values (p>0.05). OSI values of TQ, Dex, Dex-TQ groups significantly lower than those of the Control Group (p<0.05) and higher than those of the Sham Group (p<0.05 for all). There was no significant difference between TQ, Dex, Dex-TQ groups regarding to OSI values (p>0.05 for all). The histopathological damage score was the lowest in the Sham group and the highest in the Control group. While there was no significant difference between Sham, TQ, Dex, Dex-TQ groups (p>0.05); It was found to be significantly lower when compared to the control group (p<0.05). Conclusion: Histopathological changes were observed at kidney in hind limb ischemia/reperfusion due to oxidative stress. TQ and Dex had protective effects on renal tissues at ischemia/reperfusion injury.

Bacground: Predicting seminal vesicle invasion (SVI) in patients diagnosed with prostate cancer with multiparametric magnetic (mp) resonance imaging (MRI) provides more accurate local staging and thus more appropriate treatment management. Because mpMRI has a steep learning curve, radiologist experience is crucial. Our study aimed to show the difference that the experience of the uroradiologist would create in the detection rate of mpMRI and SVI by comparing it with radical prostatectomy tissue histopathology. Materials and

Background: The purpose of this study was to evaluate the relationship between initial levels of convantional liver function tests (ALT:Alanine aminotransferase; AST:Aspartate aminotransferase; GGT: gama glutamil transferase; ALP: alkaline phosphatase) and contrast induced nephropathy (CIN). Material and methods: We conducted a retrospective study of 373 subjects with acute coronary syndrome who underwent coronary angiography (CAG). According to the development of CIN, the patients were divided into two groups as those who did not develop contrast nephropathy (Group 1) and those who did (Group 2). Both groups were compared in terms of age, gender, diabetes mellitus, hypertension, estimated glomerular filtration rate (eGFR), laboratory parameters and conventional liver enzymes (ALT, AST, GGT, ALP). The patients were given isotonic solution at a rate of 1 mL/kg/hour as a standard before and after the procedure. CIN is defined as a = 0.5 mg/dL rise in serum creatinine or a 25% increase, assessed within 48-72 hours after administration of contrast medium (CM). Results: Overall, CIN developed in 104 patients (group 2 [27.8%]). Age, ALT and AST levels were significantly higher in patients who developed CIN than those without CIN (p=0.025, p<0.001, p<0.001; respectively). In correlation analysis, creatinine increase rate was positively correlated with ALT and AST levels (r = 0.161, p = 0.002; r=0.318, p=<0.001; respectively). Multivariate logistic regression analysis demonstrated that AST level was an independent predictor of CIN ( OR 1.006, 95% CI 1.003–1.009, p<0.001). Conclusions: According to study; high AST levels may predict CIN in patients who undergoing CAG.

Background: The knee is the largest joint in the human body and provides weight-bearing of the body besides locomotion. The knee joints can be deformed by fractures, osteoarthritis, or other sorts of traumas. One of the treatments is total or unicompartmental knee replacement. To have an accomplished outcome the prosthesis and the resected bone should match irreproachably. The aim of this study was to demonstrate the tibial plateau anatomy, the differences between medial and lateral condyles particularly, and provide that the Anatolian population has differences as other ethnicities have. Materials and Methods: The current study was conducted on 159 tibia bones. The bones were stored at Anatomy Department in Bursa Uludag University. The tibial plateau bones were photographed in a standardized contrivance and transferred to a digital platform. 16 different parameters on the tibial plateau were measured. The measurements were obtained using Image J software and for the statistical analyses, SPSS (ver 20.0) software was performed. Results: As the result of the statistical analyses between Byzantine and contemporary bones; statistical significance was revealed between the medial and lateral condyle. In a comparison of lateral and medial condyles area, breadth and length were greater in medial condyle in contemporary; when area, circumference, and length were greater in the medial condyle, breadth was greater in lateral condyle in Byzantine. Conclusions: To accomplish designing the optimum knee prosthesis, the prosthesis should be designed by considering the basis of differences between not only medial and lateral condyles but also populations.

Foreign body aspiration is one of the leading causes of preventable mortality and morbidity in children. Foreign body aspiration cases are most common in the first 3 years of life. Not leaving children out of adult supervision is the most important precaution for foreign body aspiration. Educating parents about first aid and the heimlich maneuver will prevent potential negative consequences. In this article, it is aimed to present a case who was brought to the emergency department in cardiac arrest after foreign body aspiration and to examine the subject of foreign body aspiration in the light of current literature.

Retinitis pigmentosa (RP) is the most common hereditary retinal degeneration. Complaints of night blindness and peripheral visual field loss are felt in the foreground. Examination findings, radiological evaluations and satisfaction in our case suggest that acupuncture can also be used in the treatment of RP disease.